FDA Breakthrough Status.
75+ Patents.
$100B+ Market Opportunity.
Built on decades of research into Galectin-3, Eliaz Therapeutics is developing a new approach designed to target a key driver of sepsis, not merely manage its symptoms. The technology has earned FDA Breakthrough Device Designation, and this is your opportunity to invest before human trials begin.
Investor Highlights
FDA Breakthrough Device Designation
Reserved for devices that may offer a more effective treatment for life-threatening conditions, this designation enables Eliaz Therapeutics more frequent interaction with the FDA and prioritized review of future regulatory submissions as XGal-3® advances toward human trials.
Published Preclinical Proof
In large-animal model of sepsis, XGal-3® demonstrated improvements in key physiological indicators within 90 minutes. The study was published in a peer-reviewed translational medicine journal and selected as its cover article.
Global MedTech Partnership
Terumo BCT a global leader in blood component and apheresis technology, is supplying the devices and disposables for Eliaz Therapeutics' clinical trials. Their distribution already reaches nearly 200 countries.
Three Decades on Galectin-3
Dr. Isaac Eliaz has spent over three decades researching Galectin-3 and its role in acute and chronic disease. He founded EcoNugenics, a science-driven company focused on Galectin-3 biology, later acquired by Charlesbank, a leading private equity firm, in 2023.
A $100B+1 Market With No Current Approved Treatment2
Sepsis treatment is our FDA entry point, a $100B market on its own. But Galectin-3 also drives disease progression in fibrosis, oncology, chronic kidney disease, and heart failure. Once adopted for sepsis, this same device (XGAL-3®) treats adjacent conditions, with 75+ patents across 30+ countries protecting that expansion. If validated clinically, this approach could represent a broader platform for modulating systemic inflammatory and fibrotic processes. The full addressable market across the U.S. and EU exceeds $300B.3
Galectin-3: The Leading Culprit Behind ICU Deaths
Sepsis is driven by a dysregulated immune response in which Galectin-3 protein plays a central role. Galectin-3 acts as your body’s fire alarm stuck in the ON position. Galectin-3 tells the immune system to attack and keep attacking even after the threat is over. This is the body’s immune response turning against itself, leading to widespread inflammation and organ failure within hours. Despite its severity, treatment remains largely supportive, managing complications rather than directly addressing the underlying biology.
Become an Eliaz Therapeutics Shareholder
Our Approach Targets and Removes Galectin-3 from the Bloodstream
XGal-3 is designed to remove circulating Galectin-3 from the bloodstream, aiming to modulate the dysregulated immune response seen in sepsis. The process is similar to dialysis: blood flows through a single-use cartridge, where Galectin-3 is selectively captured, and filtered blood is returned to the patient without adding any drugs or other agents.
The device plugs into an existing hospital apheresis infrastructure, and utilizes a proprietary antibody-coated resin, which has demonstrated high Galectin-3 binding efficiency under controlled conditions.
Our device captures Galectin-3 to mitigate the inflammatory cascade leading to organ failure.
Uses antibody-coated resin to remove Galectin-3 directly from the blood.
Designed for early ICU intervention alongside standard critical care to prevent immune collapse.
Unlike broad filters, we selectively target the specific molecule driving the chaos.
Patient-safe. Single-use. Easy adoption.
Blood is "continiously" withdrawn from patient and directed into a specialized machine.
The machine separates the blood through centrifugation, and our device captures the Galectin-3.
The purified blood is then returned to the patient's body, relieving the effects of elevated Galectin-3 levels.
Sepsis Patient Stories
Partnered with Terumo BCT For Global Collaboration & Distribution
Terumo BCT is a global leader in blood component and apheresis technologies, with a presence in nearly 200 countries. Since 2021, we have been partnered with Terumo BCT to support the development of XGal-3®. As part of this collaboration, Terumo BCT is supplying core apheresis platforms and disposables for our pre-clinical and clinical programs, enabling integration with established hospital infrastructure. This partnership provides a clear pathway to leverage existing global apheresis platforms and distribution capabilities as we advance toward commercialization.
Become an Eliaz Therapeutics ShareholderSingle-Use Design, Single Course of Care. Designed for the ICU.
Depending on the treatment protocol and patient condition, multiple columns may be used across consecutive ICU sessions, supporting repeat utilization within a single course of ICU stay.
The Path to FDA Approval
Q4 2025 – Q3 2026
Design freeze. Verification & validation testing.
Q1 2027
GLP safety studies.
Q2 – Q3 2027
First-in-human trials.
Q3 2027 – Q4 2028
Pivotal trials.
Q2 – Q3 2029
PMA submission.
Q1 2030
FDA approval.
Q2 2030
Commercial launch.
Groundbreaking Opportunity Is Priced Ahead Of Human Data
This round is intended to support GLP safety studies and first-in-human trials, with key milestones expected over the next 12–15 months.
Become an Eliaz Therapeutics ShareholderHow We’ll Use Your Investment
We're raising $3M to reach first-in-human trials and regulatory momentum.
What Investors Say
*The testimonials presented are the opinions of the individuals providing them. They may not represent the experience of all clients or investors and are not a guarantee of future performance or success.
Perks
30 Years of Galectin-3 Research
• Our founder, Dr. Isaac Eliaz, has spent over three decades researching Galectin-3 and its role in acute and chronic diseases. He founded EcoNugenics, a science-driven company focused on Galectin-3 biology, which produced an extensive body of published research and was acquired by Charlesbank, a leading private equity firm, in 2023.
• Dr. Eliaz has been researching therapeutic apheresis and offering apheresis treatments in his medical center since 2011.
• Dr. Eliaz is supported by a multidisciplinary team with experience across biomedical research, clinical development, engineering, and regulatory strategy, including experienced clinicians, scientists, and industry advisors, all contributing to the advancement of XGal-3® from concept toward clinical execution and commercialization.
MD, MS, LAc
Serial entrepreneur, clinical researcher, prior healthcare exit. Leading expertise in Gal-3 and apheresis.
MSC, MBA
Operations, Strategic partnerships, biotech commercialization
PHD
Biotech R&D leader across oncology, inflammation, and infectious disease therapeutics
MBA
Finance, Business modeling, and M&A
MBA
Background in MedTech and
HealthTech, partner to PE, VC & Founders
MD, PhD
Dr. Alpert brings decades of regulatory expertise, including 13 years at the FDA, where she served as Director of the Office of Device Evaluation (1993-1999). She will guide ETI through FDA pathways, optimizing submissions and securing key regulatory approvals for XGal-3®.
BA
Clinical operations background, support in business admin, marketing, and Investor Relations
Our World Class Scientific Advisory Board
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Professor of Medicine, Chief, Division of Nephrology at Stanford University School of Medicine
Nephrologist and Director of Hemodialysis at St.Michael's Hospital, and a Professor of Medicine at the University of Toronto
Mayo Clinic, Division of Transfusion Medicine, Professor of Laboratory Medicine & Pathology
Director of the Atherosclerosis & Lipid Apheresis Center, Associate Professor of Internal Medicine, University of Kansas Medical Center
Head of Genitourinary Oncology Unit at Tel AvivSourasky Medical Center
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What do I need to know about early-stage investing? Are these investments risky?
There will always be some risk involved when investing in a startup or small business. And the earlier you get in the more risk that is usually present. If a young company goes out of business, your ownership interest could lose all value. You may have limited voting power to direct the company due to dilution over time. You may also have to wait about five to seven years (if ever) for an exit via acquisition, IPO, etc. Because early-stage companies are still in the process of perfecting their products, services, and business model, nothing is guaranteed. That’s why startups should only be part of a more balanced, overall investment portfolio.
When will I get my investment back?
The Common Stock (the "Shares") of Eliaz Therapeutics (the "Company") are not publicly-traded. As a result, the shares cannot be easily traded or sold. As an investor in a private company, you typically look to receive a return on your investment under the following scenarios: The Company gets acquired by another company. The Company goes public (makes an initial public offering). In those instances, you receive your pro-rata share of the distributions that occur, in the case of acquisition, or you can sell your shares on an exchange. These are both considered long-term exits, taking approximately 5-10 years (and often longer) to see the possibility for an exit. It can sometimes take years to build companies. Sometimes there will not be any return, as a result of business failure.
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Shares sold via Regulation Crowdfunding offerings have a one-year lockup period before those shares can be sold under certain conditions.
Exceptions to limitations on selling shares during the one-year lockup period:
In the event of death, divorce, or similar circumstance, shares can be transferred to:
• The company that issued the securities;
• An accredited investor;
• A family member (child, stepchild, grandchild, parent, stepparent, grandparent, spouse or equivalent, sibling, mother-in-law, father-in-law, son-in-law, daughter-in-law, brother-in-law, or sister-in-law, including adoptive relationships).
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What is Eliaz Therapeutics's pre-money implied valuation?
Eliaz Therapeutics’ pre-money implied valuation is $59,436,000. The terms of this Offering are based on a pre-money using the current issued and outstanding shares of the Company (and excluding shares to be issued upon conversion of convertible securities). The Securities are priced arbitrarily and the Company makes no representations as to the reasonableness of any specified valuation.